Use "tranquillizer" in a sentence

1. a mild tranquillizer for the stomach combined with an anticholinergic to reduce the acid

2. ' Rafferty wondered if she'd even handed her husband the extra strength tranquillizer herself with a glass of water in a gesture of wifely solicitude shortly before he left the house and Sir Anthony had tossed it back without a second thought

3. Clearly the alcohol had become an effective "tranquillizer

4. Nightfall, which in the frost of winter comes as a fiend and in the warmth of summer as a lover, came as a tranquillizer on this March day