Use "vitiate" in a sentence

1. 5 A callable provision, unless at a very high premium, might entirely vitiate the value of a participating privilege

2. This one bad instance should not vitiate conclusions based on 30-odd experiments, but its recent happening gives it a special adverse weight

3. In its operation, it evidently will vitiate contracts, which ought always to be held sacred, solemnly and voluntarily entered into by the parent or guardian with the matter of an apprentice, reciprocally beneficial, founded on the most laudable and praiseworthy principles, on the faithful performance of which materially depends the future welfare of the youth, to which I believe may reasonably be added the comforts and good order of society

4. But such an interpolated composition, besides having no purpose in itself, would vitiate the unity of the entire relief